Pneumologie - Dominique Valeyre,Henry James,Pierre Duroux

Pneumologie - Dominique Valeyre,Henry James,Pierre Duroux

Pneumologie - Dominique Valeyre,Henry James,Pierre Duroux

 · Studies reporting the effects of modern strategies with pulmonary arterial hypertension (PAH)-targeted therapies in sarcoidosis-associated pulmonary hypertension (S-APH) are limited. Clinical and haemodynamic data from newly diagnosed patients with severe S-APH (mean pulmonary artery pressure (mPAP) >35 mmHg or mPAP 25–35 mmHg with cardiac index <2.5 L·min−1·m−2) were …

 · Pierre-Yves Brillet 3, Olivia Freynet 1, Nicolas Naggara 3, Zohra Carton 1, Jean-François Cordier 2, Michel Brauner 3, Dominique Valeyre 1, Hilario Nunes 1; 1 Université Paris 13, UPRES EA 2363, Assistance Publique-Hôpitaux de Paris, Hôpital Avicenne, Service de Pneumologie, Bobigny, France; 2 Hospices Civils de Lyon, Service de Pneumologie et Centre de Référence des Maladies …

Pulmonary hypertension plays an increasingly important role in contemporary medicine. It may present as discrete disease or as complication of a broad spectrum of other conditions, such as connective tissue disease, congenital heart disease, liver disease, lung disease or left heart disease. All of these forms have different features and their management is never the same.

Sarcoidosis is a systemic disease of unknown cause that is characterised by the formation of immune granulomas in various organs, mainly the lungs and the lymphatic system. Studies show that sarcoidosis might be the result of an exaggerated granulomatous reaction after exposure to unidentified antigens in individuals who are genetically susceptible.

Damien Viglino, Ingrid Jullian-Desayes, Mélanie Minoves, Judith Aron-Wisnewsky, Vincent Leroy, Jean-Pierre Zarski, Renaud Tamisier, Marie Joyeux-Faure, Jean-Louis Pépin European Respiratory Journal 49 (6) 1601923; DOI: 10.1183/13993003.01923-2016 Published 8 June 2017

Geoffrey M. Calvert, Marie H. Sweeney, James A. Morris, Marilyn A. Fingerhut, ... Denise Lafont, Francois Parquin, Gerald Simonneau, Pierre Duroux, and the Paris-Sud Lung Transplant Group. pp. 1333 – 1336. Abstract | PDF (500 KB) Role of Platelet-activating Factor in Mediating Tumor Necrosis Factor Alpha-induced Pulmonary Vasoconstriction and Plasma-Lymph Protein Transport. Christopher …

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